Your question and desired workflow isn't 100% clear to me. My interpretation: "Is there a way to create a custom mask that encapsulates a C-Script block?" to which the answer is yes. Please see the "PLECS: Creating Custom Components and Subsystem Masks" tutorial. One can pass parameters defined in the component mask into the C-Script using the C-Script's parameter field.
Please let me know if I misunderstood your question. If so, please provide a more detailed explanation, graphic, or psuedocode describing your goals.